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The BBC's Khaled Ezzelarab says this is the first time civilians have been exclusively targeted
Five people have been injured by a bomb blast close to a bus in the Egyptian capital, Cairo, the health ministry has said.
Earlier reports of a death have been discounted.
The bomb was planted on a pedestrian island and exploded as the public bus passed by in the northern district of Nasr City, a security source said.
It comes a day after the government declared the Muslim Brotherhood a terrorist organisation.
A security source has told the BBC that explosive experts detonated a second bomb that was planted in an advertising board close to where the first explosion went off in Nasr City.
The Brotherhood, whose candidate Mohammed Morsi won the presidential election in 2012 before being deposed by the military earlier this year, had already been outlawed.
In recent months, Egypt has seen a wave of attacks which the authorities have blamed on Islamist militants.
On Tuesday, 16 people were killed and more than 100 others injured in a car bomb attack on a security building in the northern city of Mansoura, officials say.
The government said the Muslim Brotherhood was behind the attack - a charge the movement denied.
An al-Qaeda-inspired militant group Ansar Beit al-Maqdis (Champions of Jerusalem) claimed responsibility.
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