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The BBC's Orla Guerin: "The target was the police"
A car bomb attack at a security building in northern Egypt has killed at least 12 people and injured more than 100, officials and state media say.
The blast led to the partial collapse of the building in the city of Mansoura, north of the capital, Cairo.
Interim Prime Minister Hazem Beblawi called it "an act of terrorism".
Attacks on the security forces have gone up since the army removed Islamist President Mohammed Morsi in July.
No group has so far claimed responsibility for Tuesday's blast.
The military-backed interim government said it was an attempt to scare people ahead of next month's referendum on a new constitution - but that the violence would not disrupt voting.
The authorities say they will strike against the guilty with an iron fist.
The Muslim Brotherhood - which supports Mr Morsi and has been banned by the interim authorities - condemned the bombing.
"Muslim Brotherhood considers this act as a direct attack on the unity of the Egyptian people," it said in a statement.
Security chief 'injured'The explosion shook the building at about 01:10 (23:10 GMT on Monday).
More than 100 people were injured. Media reports say the provincial security chief was among those hurt. Officials said most of the casualties were police officers.
The blast shattered windows of nearby buildings and its impact was felt about 20km (12 miles) away, the reports say.
Mansoura - a city of about 480,000 people - is the capital of Dakahliya province in the Nile Delta region.
Since the removal of Mr Morsi - Egypt's first democratically elected president - his supporters have been staging mass rallies demanding his immediate release.
More than 2,000 Muslim Brotherhood members have been arrested, and 450 of them on Monday went on hunger strike in protest at their "inhumane treatment".
Mr Morsi is now facing three separate criminal trials relating to his time in office.
The first trial opened on 4 November, but has been adjourned until 8 January.
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