At least 21 people have been killed by an explosion that struck a bus in the southern Syrian province of Deraa, say activist groups.
"Four children and six women [were killed] in a blast that detonated as their vehicle went past Tal al-Jumua" in the Nawa area, said the UK-based Syrian Observatory for Human Rights.
The area is in rebel-held territory but close to an army outpost.
Activists blamed regime forces for planting a bomb.
More than 100,000 people have been killed in the fighting that has ravaged Syria for two-and-a-half years - with civilians often in the firing line.
The uprising against President Bashar al-Assad's regime began in Deraa.
The Observatory said six women were also among the victims of the overnight bus blast.
A government battalion is positioned in Tal al-Jumua, "and is under siege by rebel forces. Activists blamed regime troops for planting the explosives", said the Observatory.
In other developments, the Observatory reported:
- At least 10 fighters from the al-Qaeda-linked Islamic State of Iraq and the Levant (ISIS) were killed in clashes with Kurdish fighters in the north-eastern province of Hassaka
- War planes were deployed to the eastern desert city of Deir al-Zour
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