A senior Israeli military official has said Syrian forces have used chemical weapons against rebels several times.
Brig Gen Itai Brun said military intelligence believed the nerve agent sarin had probably been used "in a number of incidents".
Syria's government and rebels have accused each other of using chemical weapons. A UN team is trying to enter Syria to investigate.
The US has said it would not tolerate the use of chemical weapons in Syria.
Speaking at a security conference in Jerusalem, Gen Brun said: "To the best of our professional understanding, the regime has made use of deadly chemical weapons against the rebels in a number of incidents in the past."
He said photographs of victims foaming at the mouth and with constricted pupils and other unspecified symptoms "provide evidence that deadly chemical weapons have been used".
"Which chemical weapons? Apparently sarin. The regime is also using chemical weapons that neutralise and are not fatal," he said.
- The CIA believes Syria has had a chemical weapons programme "for years and already has a stockpile of CW agents which can be delivered by aircraft, ballistic missile, and artillery rockets"
- Syria is believed to possess mustard gas and sarin, a highly toxic nerve agent
- The CIA also believes that Syria has attempted to develop more toxic and more persistent nerve agents, such as VX gas
- A report citing Turkish, Arab and Western intelligence agencies put Syria's stockpile at approximately 1,000 tonnes of chemical weapons, stored in 50 towns and cities
- Syria has not signed the Chemical Weapons Convention (CWC) or ratified the Biological and Toxin Weapons Convention (BTWC)
Sources: CSIS, RUSI
There has so far not been any confirmation that chemical weapons have been used during Syria's two-year-old conflict although there have been numerous accusations.
Last month, the Syrian government and rebels accused each other of using chemical weapons in an incident in Khan al-Assal in Aleppo province.
A UN team is waiting for permission from Syria to enter the country to investigate the claims.
Syria is believed to possess large amounts of chemical weapons and there has been heightened concern among the international community in recent months about the safety of the stockpiles.
On Monday, US Defence Secretary Chuck Hagel said on a visit to Israel that the use of chemical weapons by Syria against its people would be a "game-changer".
His remarks echoed a warning by President Obama in December that Syrian President Bashar al-Assad would face "consequences" if he used such weapons.
Syria has repeatedly said it would never use chemical weapons against its own citizens.
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