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The BBC's Jim Muir: "As far as we can see, this was just a random bombing"
A car bomb has exploded in the centre of Syria's capital Damascus, killing at least 15 people and wounding 47, state media reports.
The blast happened in a busy residential and commercial area, close to a school and Syria's central bank.
Huge plumes of black smoke could be seen rising over the area as the emergency services raced to the scene.
At least 70,000 people have died since the uprising against President Bashar al-Assad began just over two years ago.
UN Secretary General Ban Ki-moon said on Monday that an inspection team is in Cyprus waiting for permission to enter Syria and investigate reports of chemical weapon attacks during the conflict.
Speaking in The Hague, he said such reports "should be examined without delay, without conditions and without exceptions" but explained that the UN is still in "technical and legal" negotiations with Mr Assad's government over the team's deployment.
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Ban Ki-moon: "A technical team is in Cyprus and ready to enter Syria"
The car bomb exploded between Sabaa Bahrat Square and Shahbander street, causing extensive damage.
State television reported that 15 people had been killed and 47 had been wounded, but it is feared the toll could rise.
It is thought that children could be among the casualties.
Television footage showed bodies lying in the street and people being carried to ambulances on stretchers.
An AFP correspondent at the scene said several cars in the area were set alight by the blast which blew out windows from surrounding buildings.
Security forces and the army moved in quickly to prevent people from approaching the scene.
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